Anti-SPTAN1 antibodies are used in the immunodetection of the protein spectrin alpha, non-erythrocytic 1. In humans, the canonical protein has a reported length of 2472 amino acid residues and a mass of 284.5 kDa. Its subcellular localization is in the cytoplasm. Up to 3 different isoforms have been reported for this protein. It is notably widely expressed in many tissue types. A member of the Spectrin protein family, SPTAN1 is known to be involved with cytoskeleton organization. Post-translational modifications have been described, including protein cleavage and phosphorylation. Synonyms for this target antigen include EIEE5, NEAS, SPTA2, spectrin alpha chain, non-erythrocytic 1, alpha-II spectrin, and DEE5. SPTAN1 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Over 80 citations in the literature describe the use of SPTAN1 antibodies in research. Immunohistochemistry is a widely used application for these antibodies. Western Blot, Immunocytochemistry, and Immunofluorescence are also common applications.