SPAM1 is a symbol for the gene, Sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding), in humans. Other names include: Hyaluronidase PH-20; Hyaluronoglucosaminidase PH-20; Sperm adhesion molecule 1; Sperm surface protein PH-20; Hyal-PH20; HEL-S-96n; HYA1; HYAL5; PH-20; PH20; SPAG15. The encoded protein is an enzyme with an amino acid length of 509 and a mass of 57.8 kDa. SPAM1 is a member of the Glycosyl hydrolase 56 family. This gene shares homology with other species, including: Mouse, Rat, Zebrafish, Frog, Chicken.