Anti-SIX homeobox 1 antibodies are used for the immunodetection of the protein encoded by the SIX1 gene. In humans, the canonical protein has a reported length of 284 amino acid residues and a mass of 32.2 kDa. Its subcellular localization is in the nucleus and cytoplasm. It is notably expressed in skeletal muscle. A member of the SIX/Sine oculis homeobox protein family, it is reported to be a transcription factor that is involved in the regulation of cell proliferation, apoptosis and embryonic development (By similarity). Post-translational modifications have been described, including ubiquitination and phosphorylation. Other names for this target antigen include DFNA23, TIP39, homeobox protein SIX1, sine oculis homeobox homolog 1, and BOS3. Gene orthologs have been identified in the mouse, rat, bovine, frog, chimpanzee and chicken species. Over 130 citations in the literature describe the use of SIX homeobox 1 antibodies in research. Western Blot is a widely used application for these antibodies. In addition, ELISA is also a common application.