Anti-SIX homeobox 6 antibodies are used for the immunodetection of the protein encoded by the SIX6 gene. In humans, the canonical protein has a reported length of 246 amino acid residues and a mass of 27.7 kDa. Its subcellular localization is in the nucleus. It is reported to be expressed in the developing and adult retina. A member of the SIX/Sine oculis homeobox protein family, it is suspected to be involved in eye development. The gene encoding this protein is implicated in Optic disk anomalies with retinal and/or macular dystrophy. Other names for this target antigen include ODRMD, OPTX2, Six9, homeobox protein SIX6, homeodomain protein OPTX2, and MCOPCT2. Gene orthologs have been identified in the mouse, rat, bovine, frog, chimpanzee and chicken species. Some SIX homeobox 6 antibodies may have been used in research and have associated citations. Western Blot is a widely used application for these antibodies. ELISA, Immunocytochemistry, and Immunofluorescence are also common applications.