Anti-PTCHD1 antibodies are used in the immunodetection of the protein patched domain containing 1. In humans, the canonical protein has a reported length of 888 amino acid residues and a mass of 101.3 kDa. Its subcellular localization is in the cell membrane. Up to 3 different isoforms have been reported for this protein. It is reported to be widely expressed including in various regions of the brain with highest expression in the gray and white cerebellum, followed by the cerebellar vermis and the pituitary gland. A member of the Patched protein family, PTCHD1 is known to be required for the development and function of the thalamic reticular nucleus (TRN), a part of the thalamus that is critical for thalamocortical transmission, generation of sleep rhythms, sensorimotor processing and attention. Synonyms for this target antigen include patched domain-containing protein 1. PTCHD1 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Some PTCHD1 antibodies may have been used in research and have associated citations. Western Blot is a widely used application for these antibodies. ELISA and Immunohistochemistry are also common applications.