Anti-MMAA antibodies are used in the immunodetection of the protein metabolism of cobalamin associated A. In humans, the canonical protein has a reported length of 418 amino acid residues and a mass of 46.5 kDa. Its subcellular localization is in the mitochondria and cytoplasm. It is widely expressed across many tissue types. A member of the SIMIBI class G3E GTPase protein family, MMAA is known to be involved with metabolic processes. The MMAA gene has been associated with the disease, Methylmalonic aciduria type cblA. Synonyms for this target antigen include methylmalonic aciduria (cobalamin deficiency) cblA type, mutant adenosylcobalamin, and methylmalonic aciduria type A protein, mitochondrial. MMAA gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Immunohistochemistry is the most common application for the MMAA antibodies listed below. Western Blot and Immunofluorescence are also common applications.