Anti-PROK2 antibodies are used in the immunodetection of the protein prokineticin 2. In humans, the canonical protein has a reported length of 129 amino acid residues and a mass of 14.3 kDa. It has been described to be a secreted protein. Up to 2 different isoforms have been reported for this protein. It is reported to be expressed in the testis and, at low levels, in the small intestine. A member of the AVIT (prokineticin) protein family, PROK2 is believed to function as a an output molecule from the suprachiasmatic nucleus (SCN) that transmits behavioral circadian rhythm. The PROK2 gene has been associated with the disease, Hypogonadotropic hypogonadism 4 with or without anosmia. Synonyms for this target antigen include protein Bv8 homolog. PROK2 gene orthologs have been reported in the mouse, rat, bovine, frog, chimpanzee and chicken species. A number of PROK2 antibodies have been mentioned in research publications and have associated citations. Immunohistochemistry is a widely used application for these antibodies. ELISA and Western Blot are also common applications.