Anti-MYO10 antibodies are used in the immunodetection of the protein myosin X. In humans, the canonical protein has a reported length of 2058 amino acid residues and a mass of 237.3 kDa. Its subcellular localization is in the membrane and cytoplasm. Up to 3 different isoforms have been reported for this protein. It is ubiquitously expressed across many tissue types. A member of the Myosin protein family, MYO10 is known to be involved with the regulation of cell shape and signal transduction pathways.
The MYO10 marker can be used to identify Dorsal Excitatory Neurons.* Synonyms for this target antigen include unconventional myosin-X, unconventional myosin-10, unconventionnal myosin-X, and MyoX. MYO10 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. A number of MYO10 antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. In addition, Immunohistochemistry is also a common application.
*HuBMAP Human Reference Atlas v1.4