Anti-KIF1B antibodies are used in the immunodetection of the protein kinesin family member 1B. In humans, the canonical protein has a reported length of 1816 amino acid residues and a mass of 204.5 kDa. Its subcellular localization is in the cytoplasmic vesicles, mitochondria, and cytoplasm. Up to 4 different isoforms have been reported for this protein. It is notably widely expressed in many tissue types. A member of the Kinesin protein family, KIF1B is known to be involved with the apoptotic pathway and vesicle-mediated transport. The KIF1B gene has been associated with the disease, Charcot-Marie-Tooth disease. Synonyms for this target antigen include CMT2 and CMT2A. KIF1B gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species.