Anti-PRPS1 antibodies are used in the immunodetection of the protein phosphoribosyl pyrophosphate synthetase 1. In humans, the canonical protein has a reported length of 318 amino acid residues and a mass of 34.8 kDa. Up to 2 different isoforms have been reported for this protein. A member of the Ribose-phosphate pyrophosphokinase protein family, PRPS1 is known to catalyze the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis. The PRPS1 gene has been associated with the disease, Phosphoribosylpyrophosphate synthetase superactivity. Synonyms for this target antigen include CMTX5, DFN2, DFNX1, PPRibP, PRS-I, PRSI, ribose-phosphate pyrophosphokinase 1, and ARTS. PRPS1 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. A number of PRPS1 antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. ELISA and Immunohistochemistry are also common applications.