Anti-KLHL8 antibodies are used in the immunodetection of the protein kelch like family member 8. In humans, the canonical protein has a reported length of 620 amino acid residues and a mass of 68.8 kDa. Up to 2 different isoforms have been reported for this protein. It is notably widely expressed in many tissue types. KLHL8 is reported to be a substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex required for The BCR(KLHL8) ubiquitin ligase complex mediates ubiquitination and degradation of RAPSN. Synonyms for this target antigen include kelch-like protein 8 and kelch-like 8. KLHL8 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Western Blot is the most common application for the KLHL8 antibodies listed below. Immunofluorescence and Immunohistochemistry are also common applications.