Anti-PNPLA1 antibodies are used in the immunodetection of the protein patatin like phospholipase domain containing 1. In humans, the canonical protein has a reported length of 532 amino acid residues and a mass of 57.9 kDa. Its subcellular localization is in the cytoplasm. Up to 3 different isoforms have been reported for this protein. It is reported to be expressed in the digestive system. PNPLA1 is known to be an omega-hydroxyceramide transacylase involved in the synthesis of omega-O-acylceramides (esterified omega-hydroxyacyl-sphingosine; EOS), which are extremely hydrophobic lipids involved in skin barrier formation. The PNPLA1 gene has been associated with the disease, Ichthyosis. Synonyms for this target antigen include omega-hydroxyceramide transacylase and patatin-like phospholipase domain-containing protein 1. PNPLA1 gene orthologs have been reported in the mouse, rat, bovine, chimpanzee and chicken species. Western Blot is a widely used application for the PNPLA1 antibodies listed below. In addition, ELISA is also a common application.