Anti-PIAS2 antibodies are used in the immunodetection of the protein protein inhibitor of activated STAT 2. In humans, the canonical protein has a reported length of 621 amino acid residues and a mass of 68.2 kDa. Its subcellular localization is in the nucleus. Up to 3 different isoforms have been reported for this protein. It is reported to be mainly expressed in the testis. A member of the PIAS protein family, PIAS2 is known to function as a E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. Post-translational modifications have been described, including sumoylation. Synonyms for this target antigen include ARIP3 and DIP. PIAS2 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. A number of PIAS2 antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. ELISA and Immunohistochemistry are also common applications.