Anti-STAR antibodies are used in the immunodetection of the protein steroidogenic acute regulatory protein. In humans, the canonical protein has a reported length of 285 amino acid residues and a mass of 31.9 kDa. Its subcellular localization is in the mitochondria. It is reported to be expressed in gonads, adrenal cortex and kidney. STAR is known to play an important role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. The STAR gene has been associated with the disease, Adrenal hyperplasia. Synonyms for this target antigen include steroidogenic acute regulatory protein, mitochondrial, START domain containing 1, START domain-containing protein 1, StAR related lipid transfer (START) domain containing 1, and STARD1. STAR gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Over 140 citations in the literature describe the use of STAR antibodies in research. Immunohistochemistry is a widely used application for these antibodies. Western Blot and Immunofluorescence are also common applications.