Sphingosine kinase 1, or, SPHK1, is a human gene. Other names include: SPK 1; SK 1; SPHK. The encoded protein is an enzyme with an amino acid length of 384 and a mass of 42.5 kDa. Other isoforms may exist. This gene shares homology with other species, including: Mouse, Fly, Rat, Arabidopsis, Zebrafish, Frog, Chicken.