Anti-SGCA antibodies are used in the immunodetection of the protein sarcoglycan alpha. In humans, the canonical protein has a reported length of 387 amino acid residues and a mass of 42.9 kDa. Its subcellular localization is in the cell membrane and cytoplasm. Up to 2 different isoforms have been reported for this protein. A member of the Sarcoglycan alpha/epsilon protein family, SGCA is a known component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix. Post-translational modifications have been described, including glycosylation. Synonyms for this target antigen include ADL, DAG2, DMDA2, LGMD2D, LGMDR3, SCARMD1, adhalin, and 50DAG. SGCA gene orthologs have been reported in the mouse, rat, bovine, chimpanzee and chicken species. A number of SGCA antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. In addition, ELISA is also a common application.