Anti-sex hormone-binding globulin antibodies are used for the immunodetection of the protein encoded by the SHBG gene. In humans, the canonical protein has a reported length of 402 amino acid residues and a mass of 43.8 kDa. It is known to be a secreted protein. Alternative splicing is reported to yield 5 different isoforms for this protein. It is known to function as a androgen transport protein, but may also be involved in receptor mediated processes. Post-translational modifications have been described, including glycosylation. Other names for this target antigen include SBP, TEBG, sex steroid-binding protein, testis-specific androgen-binding protein, testosterone-binding beta-globulin, and ABP. Gene orthologs have been identified in the mouse, rat, bovine, frog, zebrafish and chimpanzee species. ELISA, Western Blot, and Immunohistochemistry are common applications for sex hormone-binding globulin antibodies.