Anti-CILK1 antibodies are used in the immunodetection of the protein ciliogenesis associated kinase 1. In humans, the canonical protein has a reported length of 632 amino acid residues and a mass of 71.4 kDa. Its subcellular localization is in the nucleus and cytoplasm. Up to 2 different isoforms have been reported for this protein. It is found to be expressed in the heart, brain, placenta, pancreas, thymus, prostate, testis, ovary, small intestine and colon, with highest levels in the placenta and testis. A member of the CMGC Ser/Thr protein kinase protein family, CILK1 is known to be required for ciliogenesis. Post-translational modifications have been described, including phosphorylation. The CILK1 gene has been associated with the disease, Endocrine-cerebroosteodysplasia. Synonyms for this target antigen include EJM10, ICK, LCK2, MRK, hICK, serine/threonine-protein kinase ICK, MAK-related kinase, and ECO. CILK1 gene orthologs have been reported in the mouse, rat, bovine, frog, chimpanzee and chicken species.