Anti-neurexin 3 antibodies are used for the immunodetection of the protein encoded by the NRXN3 gene. In humans, the canonical protein has a reported length of 637 amino acid residues and a mass of 69.3 kDa. Its subcellular localization is in the cell membrane. Alternative splicing is reported to yield 7 different isoforms for this protein. It is reported to be expressed in the blood vessel walls. A member of the Neurexin protein family, it is known to be involved with angiogenesis and signal transduction pathways. Post-translational modifications have been described, including O-glycosylation and protein cleavage. Other names for this target antigen include neurexin III, neurexin-3-alpha, and C14orf60. Gene orthologs have been identified in the mouse, rat, frog, chimpanzee and chicken species.