Anti-oligophrenin 1 antibodies are used for the immunodetection of the protein encoded by the OPHN1 gene. In humans, the canonical protein has a reported length of 802 amino acid residues and a mass of 91.6 kDa. Its subcellular localization is in the cytoplasm. Alternative splicing is reported to yield 2 different isoforms for this protein. It is reported to be expressed in the brain. It is noted to be involved in cytoskeleton organization and axon guidance. The gene encoding this protein is implicated in Intellectual developmental disorder. Other names for this target antigen include MRX60, MRXSBL, OPN1, oligophrenin-1, Rho-GTPase activating protein, and ARHGAP41. Gene orthologs have been identified in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species.