Anti-PTGDR antibodies are used in the immunodetection of the protein prostaglandin D2 receptor. In humans, the canonical protein has a reported length of 359 amino acid residues and a mass of 40.3 kDa. Its subcellular localization is in the cell membrane. Up to 2 different isoforms have been reported for this protein. It is reported to be expressed in retinal choroid, ciliary epithelium, longitudinal and circular ciliary muscles, iris, small intestine and platelet membranes. A member of the G-protein coupled receptor 1 protein family, PTGDR is a known receptor for prostaglandin D2 (PGD2). Post-translational modifications have been described, including glycosylation. The PTGDR marker can be used to identify Brain Fibroblast Non-Neuronal Cells.* Synonyms for this target antigen include ASRT1, DP, DP1, PTGDR1, PGD2 receptor, and AS1. PTGDR gene orthologs have been reported in the mouse, rat, bovine, frog and chimpanzee species.
*HuBMAP Human Reference Atlas v1.4