Anti-myotrophin antibodies are used for the immunodetection of the protein encoded by the MTPN gene. In humans, the canonical protein has a reported length of 118 amino acid residues and a mass of 12.9 kDa. Its subcellular localization is in the nucleus and cytoplasm. It is ubiquitously expressed across many tissue types. A member of the Myotrophin protein family, it is reported to promote dimerization of NF-kappa-B subunits and regulates NF-kappa-B transcription factor activity (By similarity). Other names for this target antigen include granule cell differentiation protein and protein V-1. Gene orthologs have been identified in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Some myotrophin antibodies may have been used in research and have associated citations. Western Blot is a widely used application for these antibodies. ELISA and Immunofluorescence are also common applications.