Pleckstrin homology domain containing, family G (with RhoGef domain) member 4, or Pleckstrin homology and RhoGEF domain containing G4, is a human gene encoded by PLEKHG4. It may also be known as: Puratrophin-1; Pleckstrin homology domain-containing family G member 4; PH domain-containing family G member 4; Purkinje cell atrophy-associated protein 1; ARHGEF44; PRTPHN1; SCA4. The encoded protein has an amino acid length of 1191 and a mass of 130.8 kDa. Other isoforms may exist. Homologs of this gene exist in other organisms, including: Mouse, Rat, Zebrafish, Frog, Chicken.