Anti-ISLR2 antibodies are used in the immunodetection of the protein immunoglobulin superfamily containing leucine rich repeat 2. In humans, the canonical protein has a reported length of 745 amino acid residues and a mass of 79 kDa. Its subcellular localization is in the cell membrane. ISLR2 is known to be required for axon extension during neural development. Post-translational modifications have been described, including glycosylation. Synonyms for this target antigen include leucine-rich repeat domain and immunoglobulin domain-containing axon extension protein, and immunoglobulin superfamily containing leucine-rich repeat protein 2. ISLR2 gene orthologs have been reported in the mouse, rat, bovine, zebrafish and chimpanzee species. Some ISLR2 antibodies may have been used in research and have associated citations. Western Blot is a widely used application for these antibodies. Immunofluorescence and Immunohistochemistry are also common applications.