Anti-ISL2 antibodies are used in the immunodetection of the protein ISL LIM homeobox 2. In humans, the canonical protein has a reported length of 359 amino acid residues and a mass of 39.8 kDa. Its subcellular localization is in the nucleus. ISL2 is reported to be a transcriptional factor that defines subclasses of motoneurons that segregate into columns in the spinal cord and select distinct axon pathways. Synonyms for this target antigen include ISL2 transcription factor, LIM/homeodomain, (islet-2), islet-2, and insulin gene enhancer protein ISL-2. ISL2 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Some ISL2 antibodies may have been used in research and have associated citations. Western Blot is a widely used application for these antibodies. ELISA and Immunofluorescence are also common applications.