Anti-CADM2 antibodies are used in the immunodetection of the protein cell adhesion molecule 2. In humans, the canonical protein has a reported length of 435 amino acid residues and a mass of 47.6 kDa. Its subcellular localization is in the cell membrane. Up to 5 different isoforms have been reported for this protein. It is notably expressed in the cerebellum and cerebral cortex. A member of the Nectin protein family, CADM2 is reported to be an adhesion molecule that engages in homo- and heterophilic interactions with the other nectin-like family members, leading to cell aggregation. Post-translational modifications have been described, including glycosylation. Synonyms for this target antigen include nectin-like 3, nectin-like protein 3, synaptic cell adhesion molecule 2, and immunoglobulin superfamily member 4D. CADM2 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. A number of CADM2 antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. ELISA, Immunofluorescence, and Immunohistochemistry are also common applications.