Anti-ANO6 antibodies are used in the immunodetection of the protein anoctamin 6. In humans, the canonical protein has a reported length of 910 amino acid residues and a mass of 106.2 kDa. Its subcellular localization is in the cell membrane. Alternative splicing is reported to yield 4 different isoforms for this protein. It is reported to be expressed in embryonic stem cell, fetal liver, retina, chronic myologenous leukemia and intestinal cancer. A member of the Anoctamin protein family, it is known to be involved with the transport of ions. Post-translational modifications have been described, including glycosylation. Synonyms for this target antigen include small-conductance calcium-activated nonselective cation channel, transmembrane protein 16F, and SCAN channel.