Anti-Apolipoprotein D antibodies are used for the immunodetection of the protein encoded by the APOD gene. In humans, the canonical protein has a reported length of 189 amino acid residues and a mass of 21.3 kDa. It is known to be a secreted protein. It is reported to be expressed in the liver, intestine, pancreas, kidney, placenta, adrenal, spleen, fetal brain tissue and tears. A member of the Lipocalin protein family, it is known to be involved with pathways of aging and angiogenesis. Post-translational modifications have been described, including N-glycosylation.
The apolipoprotein D marker can be used to characterize Brain Oligodendrocyte Precursor Cells and Prostatic Gland Subepithelial Connective Tissue Fibroblasts.* Gene orthologs have been identified in the mouse, rat, bovine, zebrafish, chimpanzee and chicken species. A number of Apolipoprotein D antibodies have been mentioned in research publications and have associated citations. Immunohistochemistry is a widely used application for these antibodies. Western Blot, Immunocytochemistry, and Immunofluorescence are also common applications.
*HuBMAP Human Reference Atlas v1.4