Anti-Angiopoietin 2 antibodies are used for the immunodetection of the protein encoded by the ANGPT2 gene. In humans, the canonical protein has a reported length of 496 amino acid residues and a mass of 56.9 kDa. It is known to be a secreted protein. Alternative splicing is reported to yield 3 different isoforms for this protein. It is known to bind to TEK/TIE2, competing for the ANGPT1 binding site, and modulating ANGPT1 signaling. Post-translational modifications have been described, including glycosylation. The gene encoding this protein is implicated in Lymphatic malformation. Other names for this target antigen include AGPT2 and ANG2. Gene orthologs have been identified in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Over 180 citations in the literature describe the use of Angiopoietin 2 antibodies in research. Western Blot is a widely used application for these antibodies. ELISA and Immunohistochemistry are also common applications.