Anti-amyotrophic lateral sclerosis 2 (juvenile) antibodies are used in antigen-specific immunodetection in biological samples. The target amyotrophic lateral sclerosis 2 (juvenile) is a known alias name of the protein alsin Rho guanine nucleotide exchange factor ALS2, encoded by the ALS2 gene in humans. This 1657-amino acid residue protein is believed to act as a GTPase regulator. It is reported to be widely expressed in many tissue types. Other synonyms for amyotrophic lateral sclerosis 2 (juvenile) include alsin, alsin, and ALS2, alsin Rho guanine nucleotide exchange factor.