Anti-TNXB antibodies are used in the immunodetection of the protein tenascin XB. In humans, the canonical protein has a reported length of 4244 amino acid residues and a mass of 458.4 kDa. Its subcellular localization is in the extracellular matrix and is secreted. Up to 4 different isoforms have been reported for this protein. It is reported to be highly expressed in fetal adrenal, in fetal testis, fetal smooth, striated and cardiac muscle. A member of the Tenascin protein family, TNXB is known to be involved with cytoskeleton organization and cell adhesion. Post-translational modifications have been described, including glycosylation. Synonyms for this target antigen include EDSCLL, EDSCLL1, HXBL, TENX, TN-X, TNX, TNXB1, and EDS3. TNXB gene orthologs have been reported in the mouse, bovine, frog, zebrafish and chicken species. A number of TNXB antibodies have been mentioned in research publications and have associated citations. Immunohistochemistry is a widely used application for these antibodies. ELISA and Western Blot are also common applications.