Anti-SGK1 antibodies are used in the immunodetection of the protein serum/glucocorticoid regulated kinase 1. In humans, the canonical protein has a reported length of 431 amino acid residues and a mass of 48.9 kDa. Its subcellular localization is in the cell membrane, nucleus, mitochondria, ER, and cytoplasm. Up to 5 different isoforms have been reported for this protein. It is reported to be expressed in most tissues with highest levels in the pancreas, followed by placenta, kidney and lung. A member of the AGC Ser/Thr protein kinase protein family, SGK1 is reported to be a serine/threonine-protein kinase, which is involved in the regulation of a wide variety of ion channels, membrane transporters, cellular enzymes, transcription factors, neuronal excitability, cell growth, proliferation, survival, migration and apoptosis. Synonyms for this target antigen include serine/threonine-protein kinase Sgk1, serine/threonine protein kinase SGK, and SGK. SGK1 gene orthologs have been reported in the mouse, rat, bovine, zebrafish, chimpanzee and chicken species.