Anti-SMG5 antibodies are used in the immunodetection of the protein SMG5 nonsense mediated mRNA decay factor. In humans, the canonical protein has a reported length of 1016 amino acid residues and a mass of 113.9 kDa. Its subcellular localization is in the nucleus and cytoplasm. It is ubiquitously expressed across many tissue types. SMG5 is reported to play a role in nonsense-mediated mRNA decay. Synonyms for this target antigen include LPTS-RP1, LPTSRP1, nonsense-mediated mRNA decay factor SMG5, EST1 telomerase component homolog B, EST1-like protein B, and EST1B. SMG5 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. A number of SMG5 antibodies have been mentioned in research publications and have associated citations. These antibodies are most commonly used in Western Blot experiments, among other applications.