Anti-HB3 antibodies enable researchers to detect and measure the HB3 antigen in biological samples. This target is a reported synonym of the KRT83 gene, which encodes keratin 83. This protein is known to function in pathways of aging and epidermis development, among other biological roles. The human version of HB3 has a canonical amino acid length of 493 residues and a protein mass of 54.2 kilodaltons. It is reported to be notably expressed in the hair. HB3 is a member of the Intermediate filament protein family.