Anti-SMAD1 antibodies are used in the immunodetection of the protein SMAD family member 1. In humans, the canonical protein has a reported length of 465 amino acid residues and a mass of 52.3 kDa. Its subcellular localization is in the nucleus and cytoplasm. Up to 2 different isoforms have been reported for this protein. It is ubiquitously expressed across many tissue types. A member of the Dwarfin/SMAD protein family, SMAD1 is known to be involved with the morphogenesis of anatomical structure and bone development. Post-translational modifications have been described, including ubiquitination and phosphorylation. Synonyms for this target antigen include BSP1, JV4-1, JV41, MADH1, MADR1, and BSP-1. SMAD1 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Over 1500 citations in the literature describe the use of SMAD1 antibodies in research. Western Blot is a widely used application for these antibodies. ELISA, Immunofluorescence, and Immunohistochemistry are also common applications.