Anti-PRKAA1 antibodies are used in the immunodetection of the protein protein kinase AMP-activated catalytic subunit alpha 1. In humans, the canonical protein has a reported length of 559 amino acid residues and a mass of 64 kDa. Its subcellular localization is in the nucleus and cytoplasm. Up to 2 different isoforms have been reported for this protein. It is notably expressed in many tissues, such as the appendix, urinary bladder, and adrenal gland. A member of the CAMK Ser/Thr protein kinase protein family, PRKAA1 is a known catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. Synonyms for this target antigen include AMPK alpha 1, AMPKa1, 5'-AMP-activated protein kinase catalytic subunit alpha-1, 5'-AMP-activated protein kinase, catalytic alpha-1 chain, and AMPK. Over 10000 citations in the literature describe the use of PRKAA1 antibodies in research. Western Blot is a widely used application for these antibodies. Immunofluorescence and Immunohistochemistry are also common applications.