Anti-ETS1 antibodies are used in the immunodetection of the protein ETS proto-oncogene 1, transcription factor. In humans, the canonical protein has a reported length of 441 amino acid residues and a mass of 50.4 kDa. Its subcellular localization is in the nucleus and cytoplasm. Up to 5 different isoforms have been reported for this protein. It is notably expressed in the tonsil, spleen, lymph node, bone marrow, and appendix. A member of the ETS protein family, ETS1 is known to be involved with immune response pathways and the regulation of cell proliferation.
The ETS1 marker can be used to identify Cerebral Cortex Neurons.* Synonyms for this target antigen include c-ets-1, p54, protein C-ets-1, Avian erythroblastosis virus E26 (v-ets) oncogene homolog-1, and EWSR2. ETS1 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Over 110 citations in the literature describe the use of ETS1 antibodies in research. Western Blot is a widely used application for these antibodies. ELISA, Immunofluorescence, and Immunohistochemistry are also common applications.
*HuBMAP Human Reference Atlas v1.4