Anti-HES2 antibodies are used in the immunodetection of the protein hes family bHLH transcription factor 2. In humans, the canonical protein has a reported length of 173 amino acid residues and a mass of 18.5 kDa. Its subcellular localization is in the nucleus. Up to 2 different isoforms have been reported for this protein. It is reported to be expressed in the placenta, pancreatic cancer, colon cancer with RER, cervical cancer, and in head and neck tumors. HES2 is reported to be a transcriptional repressor of genes that require a bHLH protein for their transcription. Synonyms for this target antigen include transcription factor HES-2, class B basic helix-loop-helix protein 40, hairy and enhancer of split 2, and bHLHb40. HES2 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Western Blot is the most common application for the HES2 antibodies listed below. ELISA and Immunofluorescence are also common applications.