Anti-HAPLN4 antibodies are used in the immunodetection of the protein hyaluronan and proteoglycan link protein 4. In humans, the canonical protein has a reported length of 402 amino acid residues and a mass of 42.8 kDa. Its subcellular localization is in the extracellular matrix and is secreted. It is reported to be highly expressed in the brain. A member of the HAPLN protein family, HAPLN4 is known to be important for the proper localization of brevican (BCAN), mainly as a perineuronal nets (PNNs)-type deposition in the brainstem and cerebellum thereby playing a key role in the formation and structural organization of PNNs (By similarity). Post-translational modifications have been described, including glycosylation. Synonyms for this target antigen include brain link protein 2. HAPLN4 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. A number of HAPLN4 antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. In addition, ELISA is also a common application.