IRG1 is a symbol for the gene, Immunoresponsive 1 homolog (mouse), in humans. Other names include: Cis-aconitate decarboxylase; Aconitate decarboxylase; Cis-aconitic acid decarboxylase; Immune-responsive gene 1 protein; CAD. The encoded protein is an enzyme with an amino acid length of 481 and a mass of 52.6 kDa. IRG1 is a member of the PrpD family. This gene shares homology with other species, including: Mouse, Rat, Zebrafish, Frog, Chicken.