Anti-epiphycan antibodies are used for the immunodetection of the protein encoded by the EPYC gene. In humans, the canonical protein has a reported length of 322 amino acid residues and a mass of 36.6 kDa. Its subcellular localization is in the extracellular matrix and is secreted. A member of the Small leucine-rich proteoglycan (SLRP) protein family, it is suspected to have a role in bone formation and also in establishing the ordered structure of cartilage through matrix organization. Post-translational modifications have been described, including O-glycosylation. Other names for this target antigen include PGLB, Pg-Lb, SLRR3B, dermatan sulfate proteoglycan 3, epiphycan proteoglycan, and DSPG3. Gene orthologs have been identified in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Some epiphycan antibodies may have been used in research and have associated citations. ELISA is a widely used application for these antibodies. Western Blot and Immunocytochemistry are also common applications.