Anti-TCF3 antibodies are used in the immunodetection of the protein transcription factor 3. In humans, the canonical protein has a reported length of 654 amino acid residues and a mass of 67.6 kDa. Its subcellular localization is in the nucleus. Alternative splicing is reported to yield 3 different isoforms for this protein. TCF3 is a reported transcriptional regulator involved in the initiation of neuronal differentiation and mesenchymal to epithelial transition (By similarity). Post-translational modifications have been described, including ubiquitination and phosphorylation. Synonyms for this target antigen include AGM8A, AGM8B, E2A, E47, ITF1, VDIR, bHLHb21, and AGM8.