Anti-PRKCB antibodies are used in the immunodetection of the protein protein kinase C beta. In humans, the canonical protein has a reported length of 671 amino acid residues and a mass of 76.9 kDa. Its subcellular localization is in the membrane, nucleus, and cytoplasm. Up to 2 different isoforms have been reported for this protein. It is notably expressed in many tissues, such as the lymph node and spleen. A member of the AGC Ser/Thr protein kinase protein family, PRKCB is known to be involved with adaptive immune responses and the apoptotic pathway. Post-translational modifications have been described, including phosphorylation. Synonyms for this target antigen include PKCB, PKCI(2), PKCbeta, PRKCB1, PRKCB2, protein kinase C beta type, PKC-B, and PKC-beta. PRKCB gene orthologs have been reported in the mouse, rat, bovine, frog, chimpanzee and chicken species. Over 710 citations in the literature describe the use of PRKCB antibodies in research. Western Blot is a widely used application for these antibodies. Immunofluorescence and Immunohistochemistry are also common applications.