Anti-PLCG1 antibodies are used in the immunodetection of the protein phospholipase C gamma 1. In humans, the canonical protein has a reported length of 1290 amino acid residues and a mass of 148.5 kDa. Its subcellular localization is in the cell projections. Up to 2 different isoforms have been reported for this protein. It is notably widely expressed in many tissue types. PLCG1 is known to mediate the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Synonyms for this target antigen include PLC-II, PLC1, PLC148, PLCgamma1, 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1, and NCKAP3. PLCG1 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Over 780 citations in the literature describe the use of PLCG1 antibodies in research. Western Blot is a widely used application for these antibodies. ELISA, Immunofluorescence, and Immunohistochemistry are also common applications.