PIK3CA encodes the human gene, Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha. It may also be known as: Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform; PI3-kinase subunit alpha; PI3K-alpha; PI3Kalpha; PtdIns-3-kinase subunit alpha; Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha; PtdIns-3-kinase subunit p110-alpha; p110alpha; Phosphoinositide-3-kinase catalytic alpha polypeptide; Serine/threonine protein kinase PIK3CA; CLOVE; CWS5; MCMTC; p110-alpha; phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha. The encoded protein is an enzyme with an amino acid length of 1068 and a mass of 124.3 kDa. PIK3CA is a member of the PI3/PI4-kinase family. Homologs of this gene exist in other organisms, including: Mouse, Rat, Zebrafish, Frog, Chicken.