Anti-IGKV1-27 antibodies are used in the immunodetection of the protein immunoglobulin kappa variable 1-27. In humans, the canonical protein has a reported length of 117 amino acid residues and a mass of 12.7 kDa. Its subcellular localization is in the cell membrane and is secreted. IGKV1-27 is known to be involved with adaptive immune responses.