Anti-IGSF21 antibodies are used in the immunodetection of the protein immunoglobin superfamily member 21. In humans, the canonical protein has a reported length of 467 amino acid residues and a mass of 51.8 kDa. Its subcellular localization is in the cell membrane. IGSF21 is known to be involved in synaptic inhibition in the brain. Post-translational modifications have been described, including glycosylation. The IGSF21 marker can be used to identify Interstitial Macrophages.* Synonyms for this target antigen include immunoglobulin superfamily member 21. IGSF21 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Some IGSF21 antibodies may have been used in research and have associated citations. Immunofluorescence is a widely used application for these antibodies. Western Blot and Immunohistochemistry are also common applications.
*HuBMAP Human Reference Atlas v1.4