Anti-CXCR1 antibodies are used in the immunodetection of the protein C-X-C motif chemokine receptor 1. In humans, the canonical protein has a reported length of 350 amino acid residues and a mass of 39.8 kDa. Its subcellular localization is in the cell membrane. A member of the G-protein coupled receptor 1 protein family, CXCR1 is a known receptor to interleukin-8, which is a powerful neutrophils chemotactic factor. Post-translational modifications have been described, including glycosylation. CXCR1 is also used as a cellular marker for characterizing myeloid-derived suppressor cells. Synonyms for this target antigen include C-C-CKR-1, CD128, CD181, CDw128a, CKR-1, CMKAR1, IL8R1, and C-C. CXCR1 gene orthologs have been reported in the mouse, rat and chimpanzee species. Over 240 citations in the literature describe the use of CXCR1 antibodies in research. Flow Cytometry is a widely used application for these antibodies. Western Blot and Immunohistochemistry are also common applications.