Anti-CCND3 antibodies are used in the immunodetection of the protein cyclin D3. In humans, the canonical protein has a reported length of 292 amino acid residues and a mass of 32.5 kDa. Its subcellular localization is in the nucleus and cytoplasm. Up to 4 different isoforms have been reported for this protein. It is notably expressed in many tissues, such as the bone marrow and cerebellum. A member of the Cyclin protein family, CCND3 is a reported regulatory component of the cyclin D3-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G(1)/S transition. Synonyms for this target antigen include G1/S-specific cyclin-D3 and D3-type cyclin. CCND3 gene orthologs have been reported in the mouse, rat, bovine, chimpanzee and chicken species. Over 380 citations in the literature describe the use of CCND3 antibodies in research. Western Blot is a widely used application for these antibodies. Immunofluorescence and Immunohistochemistry are also common applications.