Anti-serine and arginine-rich splicing factor 1 antibodies are used for the immunodetection of the protein encoded by the SRSF1 gene. In humans, the canonical protein has a reported length of 248 amino acid residues and a mass of 27.7 kDa. Its subcellular localization is in the nucleus and cytoplasm. Alternative splicing is reported to yield 3 different isoforms for this protein. A member of the Splicing factor SR protein family, it is reported to play a role in preventing exon skipping, ensuring the accuracy of splicing and regulating alternative splicing. Post-translational modifications have been described, including methylation and phosphorylation. Other names for this target antigen include SF2, SF2p33, SFRS1, SRp30a, serine/arginine-rich splicing factor 1, and ASF. Gene orthologs have been identified in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species.